ADH – small cell lung carcinoma & intracranial neoplasms erythropoietin - renal cell carcinoma, hemangioblastoma PTH-related peptide - squamous cell lung, renal cell, & breast carcinoma Which neoplasm is most commonly responsible for the hormone paraneoplastic syndrome? (“Blue Bloater”) - Productive cough for > 3 consecutive months in >2 years. What is the clinical definition of chronic bronchitis? What are the diagnostic criteria for major depressive episode? What changes in sleep patterns are seen in pts with depression?ĭecr slow wave sleep, Decr REM latency, Incr REM early in cycle, Incr total REM, Repeated & Early-morning awake Western blot = labeled antibody binds sample protein Northern blot = Radioactive DNA probe binds sample RNA Southern blot = Labeled DNA probe binds DNA sample Women – vaginal shortening, thinning & drynessĭescribe the probe and sample to which the probe binds in the following molecular biology techniques: Southern blot, Northern blot, and Western blot. Men – slower erection/ejaculation, longer refractory period What changes in sleep patterns and sexual anatomy are seen in the elderly? Tremor, slurring of speech, somnolence, vomiting, cerebral edema, blurring of vision What are the clinical features of hyperammonemia? High Vd (> body weight) distribute in tissues Medium Vd distribute in extracellular space or body water Volume of distribution (Vd) = amount of drug in the body / plasma drug concentration What are the leading causes of death in infants?
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